Peptide In testing8 assays
Semax 5mg
Lot Pending
Independent laboratory
Independent laboratory
HPLC purity
Pending
Result pending
Peak graph available when testing is complete
Labeled amount5mg
Measured amountPending
IdentityPending
TestedPending
Semax
Third-Party Tested
Made in the USA
Ships from the USA
Lot SEMAX-05-5218
Peptides
Semax
$65.0099.4% PurityResearch CompoundPeptidesLyophilized
Research monograph on Semax — a synthetic ACTH(4-10) analog studied for neurotrophic and cognitive signaling in preclinical models.
Strength
Quantity
1
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- HPLC & LC-MS verified purity 99%+ · Lot-linked COA
We accept:AMEXDISC●VERACH$ZV
For research use only. Not for human or animal consumption.
Molecular weight
813.92 g/mol
Molecular formula
C₃₇H₅₁N₉O₁₀S
CAS number
80714-61-0
Chain length
7 amino acids
Amino-acid sequence
Met-Glu-His-Phe-Pro-Gly-Pro
Classification: Research peptide
Batch verification
Certificate of Analysis
Independent testing with lot-specific analytical documentation.
Full GHS 16-section Safety Data Sheet for Semax, prepared per OSHA HazCom 2012 (29 CFR 1910.1200). Includes substance identity, handling & storage, PPE, stability, transport and regulatory information.
CAS No.
80714-61-0
Formula
C₃₇H₅₁N₉O₁₀S
Mol. Weight
813.92 g/mol
Classification
Not hazardous (GHS)
Semax — Research Compound Overview
Research monograph on Semax — a synthetic ACTH(4-10) analog studied for neurotrophic and cognitive signaling in preclinical models.
Research classification and format
Semax is classified on this page as a acth(4-10) regulatory peptide analog and is supplied in a lyophilized research preparation. The presentation is intended to support controlled laboratory workflows, analytical method development, and documented preclinical or in-vitro investigation appropriate to the compound.
PX1 quality and documentation
PX1 Research manufactures and finishes this product in American GMP laboratories rather than purchasing finished vials from overseas. Each released lot is evaluated through the PX1 quality program, with identity, purity, appearance, and applicable contaminant or endotoxin results documented on the lot-linked Certificate of Analysis. Researchers should review the current COA and Safety Data Sheet shown on this page before beginning work.
Laboratory handling
Store the sealed preparation at −20°C for long-term stability and protect it from light. Bring the closed vial to room temperature before opening, follow the laboratory's validated preparation protocol, and minimize repeated freeze–thaw cycles. Use calibrated equipment, document concentration and storage conditions, and follow institutional safety procedures throughout the study.
Intended use
For research use only. Not for human or veterinary use, consumption, diagnosis, treatment, or medical application. This material should be handled only by qualified professionals in an appropriate laboratory setting.
Purity (HPLC)
≥99%
Application
For Research Use only
Form
Lyophilized Powder
Storage
-20°C Long Term
Testing
Third Party Tested
Manufacture
USA
99%+ HPLC Purity
Independently verified by accredited US laboratory
Endotoxin-Screened
LAL tested, LPS-free, endotoxin report available
GMP-Certified Manufacturing
USA facility, ISO 9001:2015
Lyophilized for Stability
Shipped cold-packed and sealed for stability
Investigated in preclinical models for neurotrophic signaling, BDNF-pathway expression and cellular responses to neurological stress.
For research use only — not for human or animal consumption.
Research monograph
Semax — Complete Research Overview
What is Semax?
Semax is a synthetic heptapeptide analog of the ACTH(4-10) fragment, extended at the C-terminus with Pro-Gly-Pro to resist peptidase cleavage. Unlike the parent hormone fragment, Semax lacks corticotropic activity, which allows researchers to isolate the neurotropic component of melanocortin signaling.
PX1 Research supplies lyophilized Semax as a reference neuropeptide for cognitive, neuroprotection and BDNF-pathway research.
Mechanism of action
Semax has been reported in rodent models to elevate brain-derived neurotrophic factor and its receptor TrkB in the hippocampus, and to modulate dopaminergic and serotonergic turnover. Transcriptomic studies describe broad changes in genes related to the immune response and vascular tone following administration in ischemia models.
In laboratory comparisons Semax and Selank are studied together as the two best-characterized members of the Russian regulatory-peptide class.
Laboratory handling and storage
Semax ships as a lyophilized powder in a sealed, tamper-evident vial. Store the unopened vial between −20°C and −80°C, protected from light, until the day of use. In this state the peptide is stable through the labeled expiration date printed on the lot documentation.
Purity, testing and Certificate of Analysis
Every PX1 Research lot of Semax is manufactured in the United States and released against a documented specification of ≥99% purity by reversed-phase HPLC, with identity confirmed on the same lot by high-resolution LC-MS against the theoretical mass of the sequence.
Research use only
Semax supplied by PX1 Research is intended strictly for in-vitro laboratory and research applications. It is not a drug, food, cosmetic, or medical device, and it is not for human or veterinary use, diagnosis, treatment, or consumption.
Researchers are responsible for handling the compound in accordance with their institution's safety procedures and all applicable local regulations. Safety data sheets and current lot documentation are available on this site.
References
- Dolotov 2006. Dolotov OV, et al. Semax, an analogue of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus. Brain Research. 2006;1117(1):54-60.
All products are sold strictly for laboratory and research use only. Not for human or veterinary use, diagnosis, treatment or consumption. Statements have not been evaluated by the FDA.
High Quality — 99% Purity Guaranteed
Product Quality Guarantee
We are continuously conducting HPLC testing on all of our raw powders as well as our finished products to ensure the quality of what we ship. You can have the product you bought from us independently tested at any HPLC-licensed testing facility — and if the results come back negative, we will refund the following:
HPLC Test Fee
$100
Plus a full refund
Total order amount + shipping