Metabolic Research

Semaglutide (Research Grade)

Semaglutide is a long-acting GLP-1 receptor agonist with a fatty-acid side chain that binds albumin and extends circulating half life to roughly one week. It is the reference compound most incretin research is benchmarked against.

US cGMP Facility 99%+ HPLC Purity Public COAs Same-Day Dispatch

Shop Semaglutide

Semaglutide specifications

Reference data researchers look up before ordering semaglutide. Every lot ships with documentation matching the batch number printed on the vial.

  • Class: GLP-1 receptor agonist
  • Half life: approximately 165 hours
  • Format: lyophilized white powder
  • Storage: -20°C lyophilized, 2–8°C reconstituted

Semaglutide purity testing and certificate of analysis

Each semaglutide lot is released only after an independent purity panel. HPLC quantifies purity, LC-MS confirms molecular identity, and the lot-matched certificate is published so the number on your vial matches the report you download.

  • ≥99% HPLC purity specification
  • LC-MS mass confirmation on every batch
  • Endotoxin and sterility panel documentation
  • Lot-matched semaglutide COA published on the certifications page

Semaglutide reconstitution and BAC water ratios

Semaglutide ships lyophilized. Reconstitute with bacteriostatic water containing 0.9% benzyl alcohol. The ratios below assume a standard U-100 insulin syringe.

  • 5mg vial + 2mL BAC water = 2.5mg per mL (10 units = 250mcg)
  • 10mg vial + 2mL BAC water = 5mg per mL (10 units = 500mcg)
  • Swirl, never shake — agitation shears the peptide chain
  • Refrigerate reconstituted vials at 2–8°C, protected from light

Where to buy semaglutide

PX1 Research synthesizes and fills semaglutide in a US cGMP-compliant facility rather than reselling imported material, so purity documentation traces back to the production lot. Multi-vial pricing steps down at 3, 5 and 10 vials, and subscription intervals are available on the product page.

Reconstitution calculator

Convert vial strength and bacteriostatic water volume into exact insulin-syringe unit marks.

Peptide reconstitution calculator

Vial strength (mg)
Bacteriostatic water (mL)
Target dose

Concentration

5 mg/mL

Draw volume

0.05 mL

Insulin syringe

5 units (IU)

U-100 insulin syringe (100 units = 1 mL)

5 IU
020406080100

10 mg + 2 mL = 5 mg/mL. A 250 mcg dose = 5 units on a U-100 syringe (40 doses per vial).

For laboratory and research use only. Not for human or veterinary use.

Need solvent? Buy bacteriostatic water (10mL / 30mL)

Frequently asked questions

What is the half life of semaglutide?

Roughly 165 hours — about one week — which is why weekly-interval protocols dominate the published literature.

How much bacteriostatic water for a 5mg semaglutide vial?

2mL yields 2.5mg per mL, so 10 units on a U-100 insulin syringe equals 250mcg.

Is a certificate of analysis provided with semaglutide?

Yes. Every semaglutide lot has a published, lot-matched COA showing HPLC purity and LC-MS identity confirmation.

How should semaglutide be stored?

Store the lyophilized vial at -20°C protected from light. Once reconstituted with bacteriostatic water, keep it refrigerated at 2–8°C.

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