Repair & Recovery

TB-500 (Research Grade)

TB-500 is the synthetic active fragment of thymosin beta-4, a 43-amino-acid actin-sequestering protein. The fragment retains the actin-binding domain central to cell migration and angiogenesis research.

US cGMP Facility 99%+ HPLC Purity Public COAs Same-Day Dispatch

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TB-500 specifications

Reference data researchers look up before ordering tb-500. Every lot ships with documentation matching the batch number printed on the vial.

  • Class: actin-binding peptide fragment
  • Parent protein: thymosin beta-4 (Tβ4)
  • Half life: 2–3 hours
  • Storage: -20°C lyophilized

TB-500 purity testing and certificate of analysis

Each tb-500 lot is released only after an independent purity panel. HPLC quantifies purity, LC-MS confirms molecular identity, and the lot-matched certificate is published so the number on your vial matches the report you download.

  • ≥99% HPLC purity specification
  • LC-MS mass confirmation on every batch
  • Endotoxin and sterility panel documentation
  • Lot-matched tb-500 COA published on the certifications page

TB-500 reconstitution and BAC water ratios

TB-500 ships lyophilized. Reconstitute with bacteriostatic water containing 0.9% benzyl alcohol. The ratios below assume a standard U-100 insulin syringe.

  • 10mg vial + 2mL BAC water = 5mg per mL (10 units = 500mcg)
  • 10mg vial + 5mL BAC water = 2mg per mL (25 units = 500mcg)
  • Commonly co-reconstituted with BPC-157 in stack protocols
  • Store reconstituted at 2–8°C and use within 28 days

Where to buy tb-500

PX1 Research synthesizes and fills tb-500 in a US cGMP-compliant facility rather than reselling imported material, so purity documentation traces back to the production lot. Multi-vial pricing steps down at 3, 5 and 10 vials, and subscription intervals are available on the product page.

Reconstitution calculator

Convert vial strength and bacteriostatic water volume into exact insulin-syringe unit marks.

Peptide reconstitution calculator

Vial strength (mg)
Bacteriostatic water (mL)
Target dose

Concentration

5 mg/mL

Draw volume

0.05 mL

Insulin syringe

5 units (IU)

U-100 insulin syringe (100 units = 1 mL)

5 IU
020406080100

10 mg + 2 mL = 5 mg/mL. A 250 mcg dose = 5 units on a U-100 syringe (40 doses per vial).

For laboratory and research use only. Not for human or veterinary use.

Need solvent? Buy bacteriostatic water (10mL / 30mL)

Frequently asked questions

Is TB-500 the same as thymosin beta-4?

Not identical. TB-500 is the synthetic fragment containing the actin-binding region of the full thymosin beta-4 protein.

Why is TB-500 stacked with BPC-157?

The two are studied together because they act on different repair pathways — actin dynamics versus growth-factor and angiogenic signaling.

Is a certificate of analysis provided with tb-500?

Yes. Every tb-500 lot has a published, lot-matched COA showing HPLC purity and LC-MS identity confirmation.

How should tb-500 be stored?

Store the lyophilized vial at -20°C protected from light. Once reconstituted with bacteriostatic water, keep it refrigerated at 2–8°C.

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