5-Amino-1MQ vs SLU-PP-332: Mechanism, Specs & Reported Ranges Compared
Side-by-side comparison of 5-Amino-1MQ and SLU-PP-332 — receptor mechanism, half-life, vial sizes, reconstitution and reported study arms.
By PX1 Research Team · August 4, 2026
5-Amino-1MQ vs SLU-PP-332 at a glance
| 5-Amino-1MQ | SLU-PP-332 | |
|---|---|---|
| Class | small-molecule NNMT inhibitor | pan-ERR agonist (exercise-mimetic small molecule) |
| Reported half-life | not well characterized | not well characterized |
| Vial sizes | 5 mg vial / 50 mg capsules | 5 mg / 20 mg vial · 250 mcg capsules |
| Typical reconstitution | 5 mg + 2 mL = 2.5 mg/mL | 20 mg + 4 mL = 5 mg/mL |
| Research focus | NNMT and adipocyte-metabolism research | estrogen-related-receptor and endurance research |
Mechanistic difference
5-Amino-1MQ inhibits NNMT in adipocytes; SLU-PP-332 is a pan-ERR agonist studied as an exercise mimetic. Both are small molecules, not peptides.
Reported study ranges side by side
5-Amino-1MQ
| Study arm | Reported amount | Cadence |
|---|---|---|
| Oral arm | 50–100 mg | daily |
| Injectable arm | 2.5–5 mg | daily |
SLU-PP-332
| Study arm | Reported amount | Cadence |
|---|---|---|
| Standard arm | 250–500 mcg | daily |
Practical handling differences
Both arrive lyophilized and shelf-stable. 5-Amino-1MQ is typically prepared at 5 mg + 2 mL = 2.5 mg/mL; SLU-PP-332 at 20 mg + 4 mL = 5 mg/mL. Where half-lives differ, the literature's dosing cadence differs accordingly — longer-acting molecules are described weekly, shorter-acting ones daily or split.
Which one appears in which research context
5-Amino-1MQ shows up primarily in NNMT and adipocyte-metabolism research. SLU-PP-332 is used in estrogen-related-receptor and endurance research. They are not interchangeable substitutes; the receptor profile, not the marketing category, determines where each is used.
Documentation and sourcing
Both are supplied at ≥99% HPLC purity with lot-level COAs at /coa. Product pages: 5-Amino-1MQ · SLU-PP-332.
How PX1 documents every lot
Every PX1 lot ships with HPLC purity, LC-MS identity, residual solvent, moisture (Karl Fischer), sterility and endotoxin data. Lot documentation is published at /purity-reports, /endotoxin-reports and /coa. Synthesis, purification, lyophilization and vial fill happen in U.S. facilities — see /manufacturing-process.
Research use only. PX1 Research supplies compounds for laboratory and in-vitro research. Nothing here is medical advice, a dosing recommendation, or an offer for human or veterinary use. Figures cited are reported from published laboratory literature.