Growth-Hormone Axis Peptides: GHRH Analogs & Secretagogues
The GH axis has two inputs, and the literature separates compounds accordingly: GHRH-receptor analogs and ghrelin-receptor secretagogues. Specs, reported ranges and lot documentation for each compound.
By PX1 Research Team · August 4, 2026
Growth-Hormone Axis Peptides: GHRH Analogs & Secretagogues
The GH axis has two inputs, and the literature separates compounds accordingly: GHRH-receptor analogs and ghrelin-receptor secretagogues.
| Compound | Class | Lowest reported study amount | Vial sizes |
|---|---|---|---|
| Tesamorelin | stabilized GHRH analog | 1 mg | 10 mg |
| CJC-1295 | GHRH analog (with or without DAC) | 100 mcg | 5 mg / 10 mg |
| Sermorelin | GHRH (1-29) fragment | 200–500 mcg | 5 mg / 10 mg |
| Ipamorelin | selective ghrelin receptor (GHS-R) agonist | 200–300 mcg | 5 mg / 10 mg |
| GHRP-2 | growth hormone releasing hexapeptide | 100 mcg | 10 mg |
| GHRP-6 | growth hormone releasing hexapeptide | 100–150 mcg | 10 mg |
| Hexarelin | synthetic hexapeptide GH secretagogue | 100 mcg | 10 mg |
| MK-677 (Ibutamoren) | orally active non-peptide ghrelin mimetic | 12.5 mg | 12.5 mg capsules |
| IGF-1 LR3 | long R3 insulin-like growth factor-1 analog | 20 mcg | 1 mg |
Compound-by-compound notes
Tesamorelin
Tesamorelin is a stabilized GHRH analog studied in GHRH-axis and visceral-adipose research. Standard preparation is 10 mg + 2 mL = 5 mg/mL. Reported arms:
| Study arm | Reported amount | Cadence |
|---|---|---|
| Standard arm | 1 mg | daily |
| Extended arm | 2 mg | daily |
Product page: Tesamorelin.
CJC-1295
CJC-1295 is a GHRH analog (with or without DAC) studied in GH-pulse amplitude research. Standard preparation is 5 mg + 2 mL = 2.5 mg/mL. Reported arms:
| Study arm | Reported amount | Cadence |
|---|---|---|
| No-DAC arm | 100 mcg | 1–3× daily |
| DAC arm | 1–2 mg | weekly |
Product page: CJC-1295.
Sermorelin
Sermorelin is a GHRH (1-29) fragment studied in endogenous GH-release research. Standard preparation is 5 mg + 2 mL = 2.5 mg/mL. Reported arms:
| Study arm | Reported amount | Cadence |
|---|---|---|
| Standard arm | 200–500 mcg | nightly |
Product page: Sermorelin.
Ipamorelin
Ipamorelin is a selective ghrelin receptor (GHS-R) agonist studied in growth-hormone secretagogue research. Standard preparation is 10 mg + 2 mL = 5 mg/mL. Reported arms:
| Study arm | Reported amount | Cadence |
|---|---|---|
| Standard arm | 200–300 mcg | 1–3× daily |
Product page: Ipamorelin.
GHRP-2
GHRP-2 is a growth hormone releasing hexapeptide studied in GHS-R secretagogue research. Standard preparation is 10 mg + 2 mL = 5 mg/mL. Reported arms:
| Study arm | Reported amount | Cadence |
|---|---|---|
| Standard arm | 100 mcg | 1–3× daily |
Product page: GHRP-2.
GHRP-6
GHRP-6 is a growth hormone releasing hexapeptide studied in ghrelin-pathway and appetite-signalling research. Standard preparation is 10 mg + 2 mL = 5 mg/mL. Reported arms:
| Study arm | Reported amount | Cadence |
|---|---|---|
| Standard arm | 100–150 mcg | 1–3× daily |
Product page: GHRP-6.
Hexarelin
Hexarelin is a synthetic hexapeptide GH secretagogue studied in GH secretagogue and cardiac-model research. Standard preparation is 10 mg + 2 mL = 5 mg/mL. Reported arms:
| Study arm | Reported amount | Cadence |
|---|---|---|
| Standard arm | 100 mcg | 1–2× daily |
Product page: Hexarelin.
MK-677 (Ibutamoren)
MK-677 (Ibutamoren) is a orally active non-peptide ghrelin mimetic studied in oral GH-secretagogue research. Standard preparation is oral capsule — no reconstitution. Reported arms:
| Study arm | Reported amount | Cadence |
|---|---|---|
| Low arm | 12.5 mg | daily |
| High arm | 25 mg | daily |
Product page: MK-677 (Ibutamoren).
IGF-1 LR3
IGF-1 LR3 is a long R3 insulin-like growth factor-1 analog studied in IGF-receptor and myogenesis research. Standard preparation is 1 mg + 2 mL = 500 mcg/mL. Reported arms:
| Study arm | Reported amount | Cadence |
|---|---|---|
| Low arm | 20 mcg | daily |
| Mid arm | 50 mcg | daily |
Product page: IGF-1 LR3.
How researchers evaluate material before running anything
Purity claims mean nothing without a lot-specific COA showing an HPLC chromatogram, LC-MS identity and endotoxin results. PX1 publishes all three at /coa.
How PX1 documents every lot
Every PX1 lot ships with HPLC purity, LC-MS identity, residual solvent, moisture (Karl Fischer), sterility and endotoxin data. Lot documentation is published at /purity-reports, /endotoxin-reports and /coa. Synthesis, purification, lyophilization and vial fill happen in U.S. facilities — see /manufacturing-process.
Research use only. PX1 Research supplies compounds for laboratory and in-vitro research. Nothing here is medical advice, a dosing recommendation, or an offer for human or veterinary use. Figures cited are reported from published laboratory literature.