Sermorelin: Complete Research Guide (Specs, Reconstitution, Storage)
Sermorelin — GHRH (1-29) fragment. Specifications, reported study ranges, reconstitution math, storage rules and lot documentation.
By PX1 Research Team · August 4, 2026
What Sermorelin is
Sermorelin is a GHRH (1-29) fragment. PX1 supplies it as a lyophilized research-grade material for endogenous GH-release research, tested to ≥99% HPLC purity with LC-MS identity confirmation on every lot.
| Property | Detail |
|---|---|
| Compound | Sermorelin |
| Class | GHRH (1-29) fragment |
| Reported half-life | ~10–20 min |
| Vial sizes | 5 mg / 10 mg |
| Purity | ≥99% HPLC · LC-MS identity · COA per lot |
| Form | Lyophilized powder |
Reported study parameters
Published laboratory literature describes the following ranges. These are reported observations from research settings — not recommendations.
| Study arm | Reported amount | Cadence |
|---|---|---|
| Standard arm | 200–500 mcg | nightly |
Reconstitution
A typical preparation is 5 mg + 2 mL = 2.5 mg/mL. Add bacteriostatic water slowly down the inside wall of the vial, never directly onto the lyophilized cake, and swirl rather than shake — shear and foaming at the air-liquid interface degrade peptide structure. Run exact insulin-unit numbers for your own concentration in the peptide calculator.
Storage and stability
Sealed lyophilized Sermorelin is stable at room temperature for shipping and for 18–24 months when kept cool, dry and out of light; −20 °C is preferred for long-term storage. Once reconstituted with bacteriostatic water (0.9% benzyl alcohol), hold at 2–8 °C and observe the standard 28-day in-use window. Aliquot before freezing to avoid repeated freeze-thaw cycles, which drive aggregation and measurable purity loss.
How to verify what you received
Ask for the COA for your specific lot — not a generic PDF. A real COA carries the lot number, manufacture and retest dates, an HPLC chromatogram (not just a percentage), the LC-MS spectrum matching expected mass, and endotoxin plus sterility results. See how to read a COA.
Frequently asked questions
What purity is PX1 Sermorelin? ≥99% by HPLC, with LC-MS identity confirmation and endotoxin testing documented per lot.
What vial sizes are available? 5 mg / 10 mg.
How is it shipped? Lyophilized material is shelf-stable and ships at ambient temperature from U.S. facilities, same-day on business-day orders placed before cutoff. See shipping.
Is it made in the USA? Yes — synthesized, purified, lyophilized and vialed domestically. See /manufacturing-process.
How PX1 documents every lot
Every PX1 lot ships with HPLC purity, LC-MS identity, residual solvent, moisture (Karl Fischer), sterility and endotoxin data. Lot documentation is published at /purity-reports, /endotoxin-reports and /coa. Synthesis, purification, lyophilization and vial fill happen in U.S. facilities — see /manufacturing-process.
Product page: Sermorelin · Full catalog: /all-peptides
Research use only. PX1 Research supplies compounds for laboratory and in-vitro research. Nothing here is medical advice, a dosing recommendation, or an offer for human or veterinary use. Figures cited are reported from published laboratory literature.