Written by PX1 Research Team
PX1 chemists and research educators with hands-on experience in US-based peptide manufacturing, HPLC / mass-spectrometry lot testing, and endotoxin QC. All content is citation-backed and peer-reviewed for accuracy.
FLGR242: Modified Follistatin Research Guide (2026)
Research Guide
Reviewed By
PX1 QC — Analytical Chemistry Team
Every article is reviewed by PX1's in-house analytical team for accuracy on mechanism, dosing ranges reported in the literature, and lab-handling guidance. We do not publish clinical or medical advice.
Quick answer
FLGR242 research guide: the fragmented FST-344 construct without activin binding, albumin-binding design, research applications, and verified 5mg sourcing.
Key takeaways
- FLGR242 is a novel, fragmented and modified version of Follistatin-344 (FST-344) designed for in vitro research.
- Research applications
- FLGR242 vs native follistatin
- Sourcing FLGR242 from PX1 Research
FLGR242 is a novel, fragmented and modified version of Follistatin-344 (FST-344) designed for in vitro research. This guide explains how FLGR242 differs from native follistatin, its construct design, and what to verify before sourcing it.
What is FLGR242?
FLGR242 fuses a follistatin fragment with a patented albumin-binding peptide through a hydrophilic glycine-serine linker. Its key research difference from native follistatin is that FLGR242 does not bind activin, the interaction linked to unwanted cellular growth effects in laboratory myostatin-inhibition models.
| Property | Value |
|---|---|
| Parent protein | Follistatin-344 (FST-344) |
| Activin binding | None (by design) |
| Albumin-binding peptide | GGSGGSGGSGGRLIEDICLPRWGCLWEDD |
| Albumin binding (Kd) | <20 nM |
| Molecular weight | ~40 kDa |
| PX1 format | 5mg research vial |
Research applications
Laboratory work with FLGR242 includes myostatin-pathway studies, activin neutralization assays and TGF-β superfamily signaling with albumin-binding dynamics.
FLGR242 vs native follistatin
Native follistatin binds both myostatin and activin. FLGR242 is engineered to keep the myostatin-pathway research interest while removing activin binding, and its albumin binder extends its persistence in research systems.
Sourcing FLGR242 from PX1 Research
PX1 FLGR242 is US-manufactured with third-party HPLC and LC-MS verification. View FLGR242 at PX1 Research.
For laboratory research use only. Not for human consumption.
Frequently asked questions
What is FLGR242? A fragmented, modified Follistatin-344 construct with an albumin-binding peptide, for in vitro research.
Does FLGR242 bind activin? No — that is its main design difference from native follistatin.
What is the molecular weight of FLGR242? Approximately 40 kDa.
What size does PX1 offer? A 5mg research vial.